Cat Health · Multi-cat Household · Veterinary Medicine

Diaries of a Tired Cat Mom

I’m tired. I’m really tired and I’m using all my leftover energy to write this post. I officially have five (I almost said six) sick kitties. I only have five (as of now).

First it started with Ginger who is being extra sneezy early last week. I didn’t think it was serious since she was only doing it a few times a day so I attributed it to allergies. The weekend came and then the babies got sick on their first birthday. They got pretty bad the next day. They were breathing through their mouth, lethargic and having sneeze attacks.

Several times this week, I woke up at 2am to check on everyone and so far, only the three cats were sick.

Ginger got better, the kittens received an antibiotic shot and got most of their energy back and now the two older white sisters are sneezing and miserable. 10 days and I have five sick cats. The vet said it was a virus and will run its course between 7 to 10 days. 7 to 10 days and overlap of sneezy cats, worried cat mom and sleepless nights. Oh how I wish we could turn back time and I have five healthy cats.

I need a double shot.

Veterinary Medicine

Prednisone vs. Prednisolone

Disclaimer: I am not a licensed or certified veterinarian or medical professional. Any information taken from this blog post is purely meant for informational purposes for people who love cats. Proper medical care for your feline should be discussed with your veterinarian.

AHHH! I’ve always had a hard time trying to remember which drug (prednisone or prednisolone) my cats are on and the thought of even trying to pronounce them. Tip: Google the terms and there is an English lady teaching you how to pronounce each of them.

Apparently, they are almost the same thing. So I did a comparison of the two and this is what I found out:


  • It’s a synthetic corticosteroid.
  • It’s effective as an immunosuppressant drug.
  • Prednisone is used to treat the following:
    • Certain inflammatory diseases;
    • Some autoimmune diseases; and
    • Some types of cancers (when given at higher dosages).
  • There is a list of mild and serious side effects.


  • It’s a synthetic glucocorticoid made from hydrocortisone (cortisol).
  • It’s a steroid medication.
  • Prednisolone is used to treat the following:
    • Allergies;
    • Certain inflammatory diseases;
    • Some autoimmune disorders; and
    • Some types of cancers (when given at higher dosages).
  • There is a list of mild and serious side effects when using this medication.


By looking over the two, it appears that they are very similar. So what’s the big friggin’ difference?

Well, prednisone is ACTIVATED by enzymes in the liver to turn into prednisolone. They have similar uses, but prednisolone is more readily absorbed by the body.

A study conducted several years back compared the effectiveness of prednisone versus prednisolone in cats and dogs. What they found was that oral prednisolone was more effective and preferred when it came to treating cats.*

So, if your veterinarian prescribes prednisolone over the later, you now have a better idea on why it was prescribed!

* Source: Prednisone or Prednisolone in the Feline Patient;;